#1

I’m working on creating a top list of my favorite Rapamycin papers. I highly recommend to take a look at them if you haven’t read them. Have I missed some paper that you think are really great?

  1. “Towards disease-oriented dosing of rapamycin for longevity: does aging exist or only age-related diseases?”
    Mikhail Blagosklonny

  2. “TOR-driven aging: speeding car without brakes”
    Mikhail Blagosklonny

  3. “The hyperfunction theory of aging: three common misconceptions”
    Mikhail Blagosklonny

  4. “Lifespan benefits for the combination of rapamycin plus acarbose and for captopril in genetically heterogeneous mice”
    Randy Strong et al.

  5. “Antiaging diets: Separating fact from fiction”
    Mitchell B Lee et al.

  6. “Evaluation of off-label rapamycin use to promote healthspan in 333 adults”
    Tammi Kaeberlein et al.

  7. “Rapamycin fed late in life extends lifespan in genetically heterogeneous mice”
    Harrison D.E. et al.

  8. “mTOR inhibition improves immune function in the elderly”
    Joan Mannick et al.

  9. “Targeting the biology of aging with mTOR inhibitors”
    Joan Mannick et al.

  10. “Twenty-five years of mTOR: Uncovering the link from nutrients to growth”
    David Sabatini

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#2

“If you wait until you are ready, it is almost certainly too late.” ~Seth Godin

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#3
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#4

One paper I like to use when people are wondering what rapamycin might do for my body?

The Role of Rapamycin in Healthspan Extension via the Delay of Organ Aging By: Yan Zhang, Jinjin Zhang, Shixuan Wang

Rapamycin alleviating aging in multiple organ systems, i.e., the nervous, urinary, digestive, circulatory, motor, respiratory, endocrine, reproductive, integumentary and immune systems

Link: The Role of Rapamycin in Healthspan Extension via the Delay of Organ Aging - PubMed

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#5

It’s not an article, but Dr Attia’s podcast with Dr Klickstein is very informative.

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#6

This paper is a sobering read. From Kaeberlines’s lab.

“Despite these suggestive data, there are concerns that laboratory nutrition studies may introduce artifacts that limit translation to humans.”

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