There are some interesting issues around T and SHBG that imply that higher T, but also higher SHBG is potentially pro health.
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Tim
#284
@desertshores, I’m glad that you’ve avoided weeping and other side effects. EOD is probably a good idea. Since you got a positive response, you should double again by the next test, then maybe reach a steady state, not too high or low. Good luck to you and everyone here who is willing to self-experiment.
As I mentioned earlier I take a DIM (diindolylmethane) supplement every day. This is supposed to keep estradiol in check. If I hadn’t had the blood test I wouldn’t have known Enclomiphene/clomiphene was working. Since generally speaking I always feel good.
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Tim
#286
@JuanDaw, have you tried wasabi yourself? Does it scorch the tongue or turn into white phosphorous in the stomach? I bought some on impulse, but I regret the purchase. As you said, it ain’t cheap. And even if it works as advertised, would I notice?
Tim
#287
Yeah, me too. I’m almost always on an even keel, except when I tried the SARMS, which made my numbers too high or too low. A long paper I just read said that even when clomiphene raises T from low to normal, there’s no evidence that it improves the symptoms of low T.
Interesting new supplement I came across: Geranylgeraniol
Geranylgeraniol (GGOH) is found in edible oils such as olive, linseed, and sunflower oils.
It is also available as a supplement.
Especially important to me is its anti-sarcopenia properties and anti-inflammation properties.
It also may be of special interest to statin takers as it ameliorates the negative effects of statins.
Of course
“The MISSING Piece of the Anti-Aging Puzzle?? A Molecule Essential For Muscle, Hormone And More!!”
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Citrate hits one of the core aging pathways.
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I take a shot of EVOO every morning that I mix my polyphenol powders in. Here’s hoping.
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Radiata
#291
What is everyone doing with regard to timing of amino acids that raise mTOR, in relation to Rapamycin dose? I’ve been wary of doing taurine, glycine/creatine in the days after a rapa dose, but don’t really know how long to wait. I like taking creatine the day before my rapa dose to aid my running, but don’t know if that’s a bad idea either.
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SNK
#293
Do you know if L-Carnosine effects MTOR also?
Rapamycin much more potentially inhibits mTORc1 than any protein can activate it. That’s why I personally take rapamycin once monthly at a high dose and eat moderate-high protein every day.
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@desertshores Are you going to try it? It looks very interesting to me (a statin user). But I have to figure out what to drop from my stack if I want to try it.
Yes, it is hard to avoid the never-ending bloating of our stacks. As I have mentioned before I have a cupboard full of supplements accumulated by following whichever way the wind is blowing. I always eliminate my least favorite supplement or the one I think is doing the least good when I add a new supplement.
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Good rule. My reduction to 10 was recent so I also have a box of benchwarmers.
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Don’t let your supplements get too old! I’d use them up and then just not re-order a new batch. That’s what I’m doing right now with Fisetin and Resveratrol. But I think I have about a 2 year supply of Resveratrol… 
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Resveratrol is an HDAC inhibitor, but also a cox-1 inhibitor so i stopped taking it a few years ago.
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Did you watch the Rimon (Wellness Messiah) series on Resveratrol? He concluded that it was probably beneficial to take it but at a much reduced dose of around 100mg and perhaps only every other day. He does go into a lot of detail, as usual.
https://youtu.be/yT4rqxADvQI?si=AytZ1iKyfv1E7M4O
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Yes, I saw it. He’s the one that convinced me to take Resveratrol Mon-Wed-Fri and take about 250 mg. I originally took it daily at 500 mg.
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GG is really making a big difference. 2 weeks in and I’m feeling like my old self in power production. Keep your eye on it. Anyone else experimenting with GG?
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