#45

I have considered running NPP because of my constant elbow pain. The thing that has held me back about nandrolone is not the left ventricle hypertrophy, which I understand to be mitigated completely by telmisartin, but rather the potential cognitive impacts. But those are probably more of a risk at higher doses also.

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#47

Those were some weird posts to read before @RapMet deleted them.

Not worth any more of my attention though.

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#48

Yes so the Telmisartan should prevent possible damage by inhibiting the angiotensin pathway, which many anabolics act on, hence some of the potentially harmful effects. That’s why I keep it in my protocol.

You could go as low as 50-75mg per week of nandrolone for joint/elbow pain. I would really not expect there to be any negative health effects from that, especially if you’re also taking Telmisartan. So many people online have been doing that for very long periods of time.

I think you should choose deca over NPP. I have seen far too many people say that relieves their joint pain more than NPP, for whatever reason.

As far as people saying they get negative cognitive issues on nandrolone on Reddit, I personally haven’t noticed any at all on up to 200mg per week. Maybe all the other stuff I am doing helps too.

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#49

Yup these are the effects I see as well. I also notice a slightly more “full” look in my muscles.

I think any more than 2iu per day is probably a gamble for long term decades long use.

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#50

That does seem to be the consensus. I guess because I don’t know how I would tolerate it, and given deca’s half-life, I thought maybe NPP would be safer for an initial trial. But maybe also a waste of time. I appreciate your input!

#51

I get the logic here and normally, I would agree. I just think at the small doses we are discussing, I’d be surprised if you felt much from it neurologically.

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#52

I’ve heard that Finasteride/ Dutasteride may actually mask having prostate cancer by artificially suppressing PSA levels. Can anyone comment on this?

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#53

I’ve heard that Finasteride/ Dutasteride may actually mask having prostate cancer by artificially suppressing PSA levels. Can anyone comment on this?

Sort of the opposite, the high grade cancer is easier to detect in a smaller prostate.
Brad Stanfield explains it well in his video.

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#54
  • 6mg weekly rapamycin - EXACTLY MY DOSE !
  • 20mg atorvastatin - WHY NOT JUST 5MG OF CRESTOR
  • 5mg ezetimibe - DO YOU HAVE A GENETIC HYPERLIPIDEMIA ? MY LDL RUNS BETWEEN 70-80 ON DIET AND EXERCISE ALONE - WITHOUT LIPID RX DRUGS
  • 180mg bempedoic acid - DITTO
  • 12.5mg empagliflozin DO YOU HAVE DIABETES
  • 200mg acarbose split between 2 meals - I KNOW THAT ITP SHOWED IMPROVEMENT, BUT IS IT REALLY NECESSARY FOR THOSE EAT LOW GLYCEMIC LOADS ??? UNTIL THERE IS A HEAD TO HEAD STUDY I PERSONALLY AM NOT CONVINCED
  • 5mg tadalafil - SEE I HAVE AN ISSUE WITH THIS, THE BENEFITS IN REDUCED MORTALITY WERE IN PEOPLE WITH ED, TADALAFIL IS BASICALLY A BP LOWERING DRUG, SO UNLESS YOU ARE THAT COHORT WOULD YOU STILL GET BENEFIT WITH BP UNDER 110/60, ZERO IMPOTENCE AND CLEAN ARTERIES ???
  • 80mg telmisartan OH YOU HAVE HYPERTENSION
  • 100mg ubiquinol - IFFY
  • 200mg magnesium from glycinate YOU MEAN WITH GLYCINATE, ATTIA TAKES THIS AS DO I
  • 2g magtein OK ATTIA DOES IT TOO
  • 500mg citicoline I TAKE ALPA GPC WITH URIDINE - KEEPS ME ALERT
  • 50mg theanine - DRINK MATCHA !!!
  • methylated multivitamin - PERSONALLY I WOULD ONLY DO B VITS
  • ADK with 900mcg retinyl palmitate, 5000IU D, 1mg K1, 1.8 mg K2 - I WOULD APPLY A TOPICAL RETINOID INSTEAD, WATCH YOU D AND K2 DOSING
  • Omega 3 2 grams (triglyceride form, 2.5/1 EPA/DHA ratio) ADDRESSED IN PREVIOUS POST
  • 500mg vitamin c WHY??? THERE SHOULD A TON OF C IN YOUR DIET AND IF IT ISN’T THERE, THEN THAT’S A HUGE PROBLEM
  • 3 grams taurine YES
  • 5 grams creatine YES
  • 6 grams glycine REDUNDANT, ALSO IT’S IN COLLAGEN WHICH I WOULD SUB INSTEAD
  • 2 grams NAC - YES
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#55

I read that whole post yelling inside my brain and it was very unpleasant :sweat_smile:

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#56

:rofl: It was a quick way to differentiate the text, there is probably a way to change color of the font but I was too lazy for quick post, BTW I can get really loud at work and that’s because a lot of patients can be hard of hearing and I am tired of repeating myself.

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#57

Hmm
 solid research- thinking about starting on it?

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#62

@GregordianKnot does your multivitamin have vitamin C, K, and D in it? You could probably decrease the C, D, and Omega 3 doses.

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#68

Fascinating, thank you for sharing! I take Dutasteride so I’m assuming effects would be similar.

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#69

What is the danger if D is in range? Is there a danger from too much K2?

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#70

A post was merged into an existing topic: Hypertension drugs damage kidneys

#71

Vitamin A D E K are fat soluble so they can accumulate unlike vitamin C.
Hypervitaminosis is well known with A and D.

There is just not enough evidence of a benefit to push the vitamin dose up to the threshold for “optimal range” set between VITAMIN D,25-OH,TOTAL 30-100 ng/mL (set by Sonora Quest labs) but getting it over the insufficiency category so say over 20-30 ng/mL sounds reasonable.

When the correlation studies with low vitamin D and multiple allergy conditions started coming out 15-20 years ago, we were very excited initially. Unfortunately most intervention failed to produce any improvements in those conditions which mirrored lack of any improvement in my patients as well that were treated with VD replacement. These days I will still check the VD levels as part of urticaria, immunodeficiency, severe asthma or rhinosinusitis work up but I typically don’t bother treating unless the levels are under 30 ng/mL, otherwise their PCP can decide how to proceed.

Personally with family history of kidney stones I keep my levels of under 50 ng/mL. Apparently over 50 there is some risk developing of hypercalciuria, (over 150 there is a good chance for full on toxicity). The benefit of Vit D beyond clearing the deficiency or insufficiency range of 30 ng/mL is do dubious it just doesn’t meet benefit over risk ratio.

K2 replacement is pretty new, I think we are yet to see what would iatrogenic overdose would look like. I have zero experience with K2 personally, I know the purported benefits and it’s in Sports Research Vitamin D3 K2 with 5000iu of Plant-Based D3 & 100mcg of Vitamin K2 as MK-7 which I take 1-2 per week.

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#72

FYI: Atorvastatin is superior in terms of side effects for new onset diabetes and cataract surgery:

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#73

My D is around 50 and so I know the correct dosage to keep it these but I’ve been mega dosing K2 as part of a protocol to try to help mitigate my CVD because I didn’t realize there was a danger from dosing too high.

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#74

I didn’t say there was all I said there is for other fat soluble vitamins and K2 supplementation is relatively new.
Your risk vs benefit ration is clearly different from mine, so it MAY make sense for you.
These are tough calls we have to make

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